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Knowledge Discovery

Definition of Databases

Database Design

Biological Databases

Take Home Key Points

Practical-2 Protein Databank (PDB)

Practical-1.2 ENSEMBLE Genome Browser

Recent Update About Protein Databank

Practical -1 NCBI Nucleotide Database

What is Sequence Alignment

Some Important Terms

Types of Sequence Alignment

Dot Matrix Algorithm; How Does It Work

What is Algorithms

Dot Matrix Algorithm; Identification of Repeat Sequences

Dot Matrix Algorithm; How to Interpret The Results

Dot Matrix Algorithm; Advantages Vs Disadvantages

Dynamic Programming Method How Does It Work

Practical-3 Dot Matcher for Qualitative Comparison of Sequences (EMBOSS Tool)

How to Transform Scoring Matrix to Alignment

Practical-3 (Optional) DotMatcher for Qualitative Comparison of Sequence

Comparison Between DotMatrix and Dynamic Programming

Dynamic Programming; Some Important Terms to Understand

Practical-4 Global Pairwise Sequence Alignment Using DNA Sequences

Introduction to Database Searching; BLAST

Practical-6 Local Pairwise Sequence

Practical-5 Pairwise Sequence Alignment Using Protein

Type of Algorithms

How Does Word Algorithm Work (Part-1)

Important Statistical Values to Evaluate the BLAST Results

How Does Word Algorithm Work (Part-2)

Different Type of BLAST Associated with NCBI Databases

A Important Term For Word Algorithm

Multiple Sequence Alignment; An Introduction

Algorithms for Multiple Sequence Alignment

Optional How to Use PSI-BLAST

Progressive Sequence Alignment Algorithm

Tools for Multiple Sequence Alignment

Practical -7 How to Use BLAST Program

Practical -8 How to Use CLUSTAL-W

Practical -9 How to Use T-COFFEE

Introduction of Module 3

What Is Role of DNA

What is DNA

Algorithms for Gene Prediction-1

Where Is Our DNA is Located

What Does Gene Have

Algorithms for Gene Prediction-2

Introduction of Markov Model (Part-1)

GC-Bias and Test Code; An Ab-initio Type of Algorithm

Introduction of Markov Model (Part-2)

Machine Learning and Gene Prediction

Practical-10 Prediction of Prokaryotic Gene

Practical-10.1 Prediction of Prokaryotic Regulatory Elements

Practical-11 Prediction of Eukaryotic Gene

Introduction of Module 4

What is Protein (Part-2)

What is Protein (Part-1)

Some Important Points

Role of Amino Acids in 3D Structure

Peptide Bond; A link between Amino Acids

Double Bond like Character in Peptide Bond & Ramachandran Plot

Forces Stabilizing The Protein Structure

Secondary Structures of Proteins

Practical 13(B) Visulization of Protein Structure in Chimera (Part-2)

Practical 13 Visualization of Protein Structure in Pymol

Why Protein Structure Prediction is So Important

Practical 13(A) Visulization of Protein Structure in Chimera (Part-1)

Protein Secondary Structure Prediction Algorithms (Part-1)

Practical-15 Prediction of Globular Protein Secondary Structure

Algorithm for Secondary Structure Prediction of Transmembrane Proteins

Practical-16 Prediction of Transmembrane Helix Secondary Structure

Protein Secondary Structure Prediction Algorithms (Part-2)

D Structure Prediction Algorithms

Homology Based Algorithm (Part-1)

Homology Based Algorithm (Part-2)

Homology Based Algorithm (Part-3)

Homology Based Algorithm (Part-4)

Modeller access in MAC

Model Validation & Draw back of Homology Based Algorithm

Threading Algorithm for 3D Structure Prediction

(Very Important) Practical Learn How to Use Alpha-Fold 2

Practical-18 Prediction of 3D structure Using Threading Technique (I-TASSER)

(Optional) Practical-18.1 Use of InterPro

How to Make Publication Quality Images In Pymol (Very Important)

Practical Learn How to Use Alpha-Fold3

Practical-17 Prediction of 3D structure Using Homology Modeling (Mdeller)

Update Another GOR-IV Server for Secondary Structure Predictions

(Optional) Practical-20 How to Perform Docking Easily Using Vina

(Optional) Practical-21 How to Analyze the Docking Data

(Optional) Practical 3 ZINC Database for Drug Searching

Some Important Terms To Understand Phylogenetic Tree

Different Type of Phylogenetic Trees

What is Evolution and Phylogenetics

Steps To Construct Phylogenetic Tree

Alignment for Tree Construction

Selection of Molecular Marker for Tree Construction

Evolutionary Model Selection

Validation of Tree By Bootstrapping

Methods To Construct Tree

Practical -19 Building Phylogenetic Tree

Practical-19.1 Building Beautiful Circular Phylogenetic Tree